Table 4. Characteristics between subtypes of breast cancer combining ER, PR and HER2*.
| Luminal A (n = 1761) | P | Luminal B (n = 451) | HER2+ (n = 285) | TNBC (n = 734) | ||||
| N (%) | pbonferroni | N (%) | pbonferroni | N (%) | pbonferroni | |||
| Median age& | 48.0 | 0.06 | 47.0 | 50.0 | 48.0 | |||
| Median BMI& (kg/m2) | 23.1 | 0.01 | 23.1 | 0.99 | 23.4 | 0.99 | 22.6 | 0.01 |
| Classification of BMI& (kg/m2) | 0.01 | 0.99 | 0.99 | 0.006 | ||||
| <18.5 | 53 (3.5) | 12 (2.9) | 8 (3.1) | 30 (4.9) | ||||
| <23.0 | 686 (44.6) | 189 (46.1) | 111 (42.9) | 315 (50.9) | ||||
| <25.0 | 346 (22.5) | 88 (21.5) | 60 (23.2) | 117 (18.9) | ||||
| ≥25.0 | 452 (29.4) | 121 (29.5) | 80 (30.9) | 157 (25.4) | ||||
| Menopausal status# | <0.05 | 0.30 | 0.12 | 0.99 | ||||
| Pre-menopause | 1101 (62.5) | 301 (66.7) | 159 (55.8) | 444 (60.5) | ||||
| Post-menopause | 660 (37.5) | 150 (33.3) | 126 (44.2) | 290 (39.5) | ||||
| Median age at menopause& | 50.0 | 0.38 | 50.0 | 50.0 | 50.0 | |||
| Median age of first living birth& | 25.0 | 0.25 | 25.0 | 24.0 | 25.0 | |||
| Parity& | 0.08 | |||||||
| 0 | 48 (2.9) | 7 (1.7) | 2 (0.7) | 14 (2.0) | ||||
| 1 | 832 (49.7) | 222 (52.2) | 121 (45.0) | 336 (48.0) | ||||
| >1 | 795 (47.5) | 196 (46.1) | 146 (54.3) | 350 (50.0) | ||||
| Breastfeeding# | 0.95 | |||||||
| Yes | 1093 (90.5) | 2901 (91.2) | 175 (91.6) | 440 (90.7) | ||||
| No | 115 (9.5) | 28 (8.8) | 16 (8.4) | 45 (9.3) | ||||
| Family BC history# | <0.05 | 0.18 | 0.99 | 0.52 | ||||
| No | 1669 (96.0) | 426 (97.9) | 264 (97.1) | 684 (94.7) | ||||
| Yes | 70 (4.0) | 9 (2.1) | 8 (2.9) | 38 (5.3) | ||||
*
pbonferroni = 3×p-value in comparisons with subtype of ER+/PR+;
&
Wilcoxon test;
#
Chi-square test.