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. 2013 Aug 20;8(8):e72584. doi: 10.1371/journal.pone.0072584

Table 1. Plasma proteins identified with high confidence in all the three workflows.

Accession Gene Symbol Description Unique peptides MW [kDa] Calc. pI Localization Comparison with Schenk et al. (Ref 10)a Comparison with Anderson et al (Ref 8) a Biological Process
IPI:IPI00006114.5 SERPINF1 Pigment epithelium-derived factor 13 46.3 6.38 Extracellular + + Cell communication; Signal transduction
IPI:IPI00007199.4 SERPINA10 Protein Z-dependent protease inhibitor 7 55.1 7.64 Extracellular + + Protein metabolism
IPI:IPI00009865.4 KRT10 Keratin, type I cytoskeletal 10 24 58.8 5.21 Cytoplasm + − Cell growth and/or maintenance
IPI:IPI00010295.1 CPN1 Carboxypeptidase N catalytic chain 8 52.3 7.34 Extracellular + + Protein metabolism
IPI:IPI00011252.1 C8A Complement component C8 alpha chain 13 65.1 6.47 Extracellular + + Immune response
IPI:IPI00017601.1 CP Ceruloplasmin 50 122.1 5.72 Extracellular + + Metabolism; Energy pathways
IPI:IPI00019399.2 SAA4 Serum amyloid A-4 protein 2 14.7 9.07 Extracellular + + Transport
IPI:IPI00019568.1 F2 Prothrombin (Fragment) 32 70 5.9 Extracellular + + Protein metabolism
IPI:IPI00019576.1 F10 Coagulation factor X 4 54.7 5.94 Extracellular + + Protein metabolism
IPI:IPI00019580.1 PLG Plasminogen 45 90.5 7.24 Extracellular + + Protein metabolism
IPI:IPI00019591.2 CFB cDNA FLJ55673, highly similar to Complement factor B 41 140.9 7.18 Extracellular + − Immune response
IPI:IPI00019943.1 AFM Afamin 22 69 5.9 Extracellular + − Cell growth and/or maintenance
IPI:IPI00020996.5 IGFALS Insulin-like growth factor-binding protein complex acid labile subunit 12 66 6.79 Extracellular + + Cell communication; Signal transduction
IPI:IPI00021842.1 APOE Apolipoprotein E 18 36.1 5.73 Extracellular + + Transport
IPI:IPI00022229.2 APOB Apolipoprotein B-100 190 515.3 7.05 Extracellular + + Transport
IPI:IPI00022371.1 HRG Histidine-rich glycoprotein 16 59.5 7.5 Extracellular + + Apoptosis
IPI:IPI00022391.1 APCS Serum amyloid P-component 11 25.4 6.54 Extracellular + + Protein metabolism
IPI:IPI00022395.1 C9 Complement component C9 18 63.1 5.59 Extracellular + + Immune response
IPI:IPI00022417.4 LRG1 Leucine-rich alpha-2-glycoprotein 13 38.2 6.95 Extracellular + + Biological_process unknown
IPI:IPI00022488.1 HPX Hemopexin 24 51.6 7.02 Extracellular + + Transport
IPI:IPI00022895.7 A1BG Alpha-1B-glycoprotein 13 54.2 5.87 Extracellular − − Biological_process unknown
IPI:IPI00022895.8 A1BG Isoform 1 of Alpha-1B-glycoprotein 15 54.2 5.86 Extracellular + − Biological_process unknown
IPI:IPI00026199.2 GPX3 Glutathione peroxidase 3 5 25.5 8.05 Extracellular + + Metabolism; Energy pathways
IPI:IPI00027827.2 SOD3 Extracellular superoxide dismutase [Cu-Zn] 4 25.8 6.61 Extracellular + − Metabolism; Energy pathways
IPI:IPI00029193.1 HGFAC Hepatocyte growth factor activator 7 70.6 7.24 Extracellular + + Protein metabolism
IPI:IPI00029717.1 FGA Isoform 2 of Fibrinogen alpha chain 23 69.7 8.06 Extracellular − − Protein metabolism
IPI:IPI00029739.5 CFH Isoform 1 of Complement factor H 49 139 6.61 Extracellular + − Immune response
IPI:IPI00032179.3 SERPINC1 Antithrombin-III 31 52.6 6.71 Extracellular + + Protein metabolism
IPI:IPI00032220.3 AGT Angiotensinogen 13 53.1 6.32 Extracellular + + Cell communication; Signal transduction
IPI:IPI00032291.2 C5 Complement C5 44 188.2 6.52 Extracellular + + Immune response
IPI:IPI00032293.1 CST3 Cystatin-C 1 15.8 8.75 Extracellular + + Protein metabolism
IPI:IPI00032311.4 LBP Lipopolysaccharide-binding protein 5 53.3 6.7 Extracellular + + Immune response
IPI:IPI00163207.1 PGLYRP2 Isoform 1 of N-acetylmuramoyl-L-alanine amidase 13 62.2 7.55 Extracellular + − Immune response
IPI:IPI00166729.4 AZGP1 Zinc-alpha-2-glycoprotein 21 34.2 6.05 Extracellular + + Immune response
IPI:IPI00215983.3 CA1 Carbonic anhydrase 1 6 28.9 7.12 Cytoplasm + − Metabolism; Energy pathways
IPI:IPI00218413.2 BTD Biotinidase 5 61.1 6.25 Extracellular + + Metabolism; Energy pathways
IPI:IPI00218732.4 PON1 Serum paraoxonase/arylesterase 1 8 39.7 5.22 Extracellular + + Metabolism; Energy pathways
IPI:IPI00219713.1 FGG Isoform Gamma-A of Fibrinogen gamma chain 20 49.5 6.09 Extracellular − − Protein metabolism
IPI:IPI00292530.1 ITIH1 Inter-alpha-trypsin inhibitor heavy chain H1 29 101.3 6.79 Extracellular + + Protein metabolism
IPI:IPI00292946.1 SERPINA7 Thyroxine-binding globulin 11 46.3 6.3 Extracellular + + Protein metabolism
IPI:IPI00294395.1 C8B Complement component C8 beta chain 16 67 8.13 Extracellular + + Immune response
IPI:IPI00296099.6 THBS1 Thrombospondin-1 7 129.3 4.94 Extracellular + + Cell growth and/or maintenance
IPI:IPI00296537.4 FBLN1 Isoform C of Fibulin-1 12 74.4 5.24 Extracellular + − Cell growth and/or maintenance
IPI:IPI00296608.6 C7 Complement component C7 21 93.5 6.48 Extracellular + + Immune response
IPI:IPI00298497.3 FGB Fibrinogen beta chain 24 55.9 8.27 Extracellular + + Protein metabolism
IPI:IPI00298971.1 VTN Vitronectin 12 54.3 5.8 Extracellular + + Cell growth and/or maintenance
IPI:IPI00299503.2 GPLD1 Isoform 1 of Phosphatidylinositol-glycan-specific phospholipase D 12 92.3 6.37 Extracellular + − Cell communication; Signal transduction
IPI:IPI00304273.2 APOA4 Apolipoprotein A-IV 38 45.4 5.38 Extracellular + + Transport
IPI:IPI00306378.5 MASP2 Isoform 2 of Mannan-binding lectin serine protease 2 1 20.6 5.96 Extracellular − − Protein metabolism
IPI:IPI00328609.3 SERPINA4 Kallistatin 16 48.5 7.75 Extracellular − − Protein metabolism
IPI:IPI00418163.3 C4B Complement C4-B preproprotein 64 192.6 7.27 Extracellular + − Immune response
IPI:IPI00478809.4 F5 Coagulation factor V 23 251.5 6.05 Extracellular − + Protein metabolism
IPI:IPI00479723.5 FN1 Isoform 10 of Fibronectin 22 239.5 5.88 Extracellular − − Cell growth and/or maintenance
IPI:IPI00480192.1 RTN4RL2 Retinol binding protein 4, plasma 10 22.9 6.09 Plasma membrane − − Cell communication; Signal transduction
IPI:IPI00555812.5 GC Vitamin D-binding protein isoform 1 precursor 34 52.9 5.45 Extracellular + − Transport
IPI:IPI00556459.2 SERPING1 cDNA FLJ58564, highly similar to Plasma protease C1 inhibitor 14 49.7 6.54 Extracellular − − Protein metabolism
IPI:IPI00643948.2 C1QB Complement component 1, q subcomponent, B chain 4 24.4 9.16 Extracellular − − Immune response
IPI:IPI00656111.1 PRG4 Isoform E of Proteoglycan 4 6 102.4 9.63 Extracellular − − Cell growth and/or maintenance
IPI:IPI00794777.1 PRDX2 Uncharacterized protein 2 15.1 6.13 Plasma membrane − − Metabolism; Energy pathways
IPI:IPI00795633.1 CLU CLU 18 52.3 6.38 Extracellular − − Immune response
IPI:IPI00815947.1 SERPING1 Truncated beta-globin (Fragment) 2 4.5 9.47 Extracellular − − Protein metabolism
IPI:IPI00847635.1 SERPINA3 Isoform 1 of Alpha-1-antichymotrypsin 23 47.6 5.52 Extracellular − − Protein metabolism
IPI:IPI00879573.1 SERPIND1 Heparin cofactor 2 22 57 6.9 Extracellular − + Protein metabolism
IPI:IPI00879709.3 C6 Complement component 6 precursor 28 105.7 6.79 Extracellular − − Immune response
IPI:IPI00887739.3 C3 complement C3-like, partial 7 144.7 7.52 Extracellular − − Immune response
IPI:IPI00910249.1 COMP cDNA FLJ59562, highly similar to Cartilage oligomeric matrix protein 2 77.2 4.53 Extracellular − − Cell growth and/or maintenance
IPI:IPI00922213.2 FN1 cDNA FLJ53292, highly similar to Homo sapiens fibronectin 1 (FN1), transcript variant 5, mRNA 4 111.2 6.21 Extracellular − − Cell growth and/or maintenance
IPI:IPI00939169.1 ATRN Isoform 3 of Attractin 4 133.6 6.98 Extracellular − − Immune response
IPI:IPI00966295.1 Light chain of factor I 16 65 7.5 − −
IPI:IPI00967977.2 CD14 Conserved hypothetical protein 5 31.7 6.29 Extracellular − − Immune response
a

The symbols+and–indicate presence and absence of a protein when compared our dataset with the dataset by Schenk et al. [10] and Anderson et al. [8] study.