Skip to main content
. 2013 Aug 20;8(8):e71880. doi: 10.1371/journal.pone.0071880

Table 1. A summary of published findings of DA-induced changes in neuronal excitability recorded from rat PFC neurons of different postnatal ages [4], [26], [27], [29], [30], [41][43], [78][89].

Published Studies Age Animal Neuronal types Treatment Effect on single neuronal excitability
Bandyopadhyay S et al., 2005 25–30 d Rat PFC pyramidal cell layer II/III SKF81297 increase
Ceci A et al., 1999 150–250 g Rat PFC pyramidal cell DA increase
Chen et al., 2007 27–36 d Rat PFC layer V/VI pyramidal cell SKF81297 increase
Geijo-Barrientos E et al., 1995 150–200 g Rat PFC pyramidal cell DA decrease
Gorelova & Yang, 2000 35–49 d Rat PFC layer V/VI pyramidal cell SKF81297 increase
Gulledge AT & Jaffe DB., 2001 17–30 d Rat PFC layer V pyramidal cell DA increase
Gulledge AT et al., 1998 17–30 d Rat PFC layer V pyramidal cell DA decrease
Henze DA et al., 2000 Young Monkey PFC layer V pyramidal cell DA increase
Lavin A et al., 2005 250–300 g Rat PFC deep layer pyramidal cell VTA stimulation increase
Lavin, A & Grace, AA, 2001 14–21 d Rat PFC deep layer pyramidal cell SKF38393 increase
Moore A et al., 2011 19–32 d Rat PFC layer V pyramidal cell DA increase
Di Pietro & Seamans 2011 21–35 d Rat PFC pyramidal cell DA increase
Penit-Soria J et., 1987 18–23 d Rat PFC layer III/V/VI pyramidal cell DA increase
Rotaru DC et al., 2007 19–28 d Rat PFC layer V pyramidal cell SKF81297 decrease
Seamans JK et al., 2001 14–28 d Rat PFC layer V interneuron DA bidireactional
Seong & Carter, 2012 21–28 d Mice PFC layer V D1+ve pyramidal cell SKF38393 increase
Thurley et al., 2008 17–44 d Rat PFC layer V pyramidal cell SKF38393 increase
Tseng & O’Donnell, 2004 42–65 d Rat PFC layer V/VI pyramidal cell SKF81297 increase
Wang & O’Donnell, 2001 24–28 d Rat PFC layer V pyramidal cell SKF38393 increase
Yang CR, Seamans JK, 1996 80–100 g Rat PFC layer V/VI pyramidal cell SKF81297 increase