Figure 2. Absolute maximal force production (A), specific (B) and relative (C) force production during the force-frequency protocol and specific force production during the stimulation protocol (D) in WT group (•) and Tg(ACTA1)^Asp286Gly group (○).

Force was normalized to hindlimb muscles volume (B, D) and to maximal force obtained at 150 Hz (C). f₅₀ (inset Figure C) represents the frequency resulting in half the maximal force production. Absolute (A) and specific force production (B & D) were lower in Tg(ACTA1)^Asp286Gly group as compared to the WT group. On the contrary, no difference was observed for f₅₀ between the two groups. Values are presented as the mean ± SEM. Significantly different between groups * P < 0.05.