Table 4.
Radiologic Features of Highly-aggressive HPV+ Oropharyngeal Cancers
| Primary Tumor | Cervical Lymph Nodes | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Case # | ∼ Volume (mL) |
SUV |
Level of largest LN |
Largest dimension (cm) |
∼Volume (mL) |
Ipsilateral LNs |
SUV | ECS | CTN | Clustering |
| 1 | 6.1 | NR | IIa/IIb | 4.7 | 42.8 | 20 | II, V | + | + | + |
| 2 | 49.2 | 14 | IIb | 2.9 | 12.2 | 14 | I−III | + | + | + |
| 3 | 24.0 | 15 | IIa/IIb | 3.5 | 30.2 | 13 | I−VI | + | + | + |
| 4 | 4.1 | NR | IIa | 3.3 | 24.1 | 14 | II−III | + | − | + |
| 5 | 73.0 | 26 | IIa | 5.2 | 51.4 | 12 | II, IV | + | + | + |
| 6 | 6.1 | NR | DTA | DTA | DTA | DTA | DTA | DTA | DTA | DTA |
| 7 | 5.2 | 9 | IIa | 2.5 | 8.0 | 9 | II | + | + | + |
ECS, Extracapsular spread; CTN, central tumor necrosis; SUV, standard uptake value; NR, not recorded; LN, lymph node; DTA, difficult to assess as patient had prior radiation therapy to necks