Table 5. Emax and log EC50 values of vasodilator responses to DEA-NO in control, ketotifen-incubated (0.1 µmol/L) or tranilast-incubated.
(0.1 mmol/L mesenteric arteries from Wistar rats before and after preincubation with tempol (0.1 mmol/L).
| Untreated | Tempol-treated | |||
| Emax | log EC50 | Emax | log EC50 | |
| Control | 101.5 + 2.16 | -5.39 + 0.04 | 94.76 + 7.52 | -6.10 + 0.18# |
| Ketotifen | 99.11 + 8.40 | -6.14 + 0.18* | 101.10 + 2.38 | -5.95 + 0.15 |
| Tranilast | 98.02 + 2.44 | -6.33 + 0.07* | 98.62 + 3.03 | -6.38 + 0.08 |
Results are expressed as means + S.E.M. n= 6 animals each group. *P < 0.05 vs. control segments. #P< 0.05 tempol incubated vs. unincubated segments.