Table 1.
Antibodies to HE4 in sera from women with various types of infertility compared to normal controls.
| Positive sera at dilution 1:20 | Positive sera at dilution 1:100 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Serum donor | n | M+2SD | M+3SD | n | M+2SD | M+3SD | ||||
| N | % pos | n | % pos | n | % pos | n | % pos | |||
| Normal controls | 131 | 3 | 2 | 1 | 1 | 82 | 1 | 1 | 1 | 1 |
| Unexplained Infertility. | 47 | 6 | 13 | 3 | 6 | 37 | 0 | 0 | 0 | 0 |
| POF | 26 | 8 | 31*** | 6 | 24*** | 15 | 2 | 13* | 2 | 13* |
| Ovulatory dysfunction | 17 | 8 | 47** | 8 | 47** | 5 | 2 | 40** | 1 | 20 |
| Endometriosis | 23 | 4 | 17** | 0 | 0 | 22 | 0 | 0 | 0 | 0 |
|
| ||||||||||
| ALL | 113 | 26 | 23*** | 17 | 15*** | 79 | 4 | 5 | 2 | 3 |
*
p<0.05
**
p<0.01
***
p<0.001