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. Author manuscript; available in PMC: 2014 Aug 1.

Published in final edited form as: Mol Cancer Res. 2013 May 10;11(8):923–936. doi: 10.1158/1541-7786.MCR-12-0686

miR-155−/− macrophages promote tumor cell migration and proliferation. A, Transwell migration assay of LLC cells migrating towards WT and miR-155−/− MΦ treated with SFM and LLC-CM. Representative fluorescence images of migrated LLC cells. Calcein was used to stain the cells. Magnification, 200 ×. B Data were presented as the mean ± SEM of 20 fields/group. **, p<0.001 by Student's t test. C, [³H] Thymidine incorporation assay of LLC cell proliferation. LLC cells were transfected with Negative control (con inhibitor) and mir155 inhibitor for 24 h and were cocultured with WT MΦ and miR-155−/− MΦ for another 48 h. Data are represented as the mean ± SEM (n=6 per group). **, p<0.001 by Student's t test.

miR-155−/− macrophages promote tumor cell migration and proliferation. A, Transwell migration assay of LLC cells migrating towards WT and miR-155−/− MΦ treated with SFM and LLC-CM. Representative fluorescence images of migrated LLC cells. Calcein was used to stain the cells. Magnification, 200 ×. B Data were presented as the mean ± SEM of 20 fields/group. **, p<0.001 by Student's t test. C, [³H] Thymidine incorporation assay of LLC cell proliferation. LLC cells were transfected with Negative control (con inhibitor) and mir155 inhibitor for 24 h and were cocultured with WT MΦ and miR-155−/− MΦ for another 48 h. Data are represented as the mean ± SEM (n=6 per group). **, p<0.001 by Student's t test.