Table 2.
Risk Factors Associated with Pericardial Fat and Intra-Thoracic Fata
Pericardial Fat Beta (95% CI) |
p-value | Intra-Thoracic Fat Beta (95% CI) |
p-value | |
---|---|---|---|---|
Age, years | 0.36 (0.11, 0.60) | 0.004 | 0.31 (0.11, 0.50) | 0.002 |
Sex/Ethnic Group | ||||
White Men | ref | -- | ref | -- |
White Women | −9.93 (−15.62, −4.25) | 0.001 | −17.79 (−22.33, −13.25) | <0.001 |
Filipina Women | 5.25 (−0.53, 11.04) | 0.07 | −17.88 (−22.49, −13.26) | <0.001 |
African-American Women | −20.12 (−25.63, −14.61) | <0.001 | −28.60 (−33.00, −24.21) | <0.001 |
Body Mass Index, kg/m2 | 1.76 (1.27, 2.26) | <0.001 | 1.29 (0.90, 1.69) | <0.001 |
Ever Smoking | ||||
Yes | 3.84 (0.47, 7.20) | 0.03 | 2.01 (−0.67, 4.69) | 0.14 |
No | ref | -- | ref | -- |
Exercise ≥ 3x/week | ||||
Yes | −2.66 (−6.32, 1.01) | 0.16 | −0.71 (−3.63, 2.22) | 0.64 |
No | ref | -- | ref | -- |
Prevalent Hypertensionb | ||||
Yes | 1.25 (−2.10, 4.60) | 0.47 | 2.05 (−0.62, 4.73) | 0.13 |
No | ref | -- | ref | -- |
Prevalent Diabetesb | ||||
Yes | −3.05 (−8.10, 2.00) | 0.25 | −2.26 (−6.29, 1.76) | 0.27 |
No | ref | -- | ref | -- |
HDL cholesterol, mg/dL | −0.12 (−0.24, 0.01) | 0.07 | −0.06 (−0.16, 0.04) | 0.27 |
LDL cholesterol, mg/dL | 0.07 (0.02, 0.12) | 0.005 | 0.04 (0.00, 0.08) | 0.03 |
Triglycerides, mg/dL | 0.05 (0.03, 0.08) | <0.001 | 0.02 (0.00, 0.05) | 0.03 |
Interleukin-6, pg/mL | 0.79 (−0.03, 1.60) | 0.06 | 0.24 (−0.41, 0.89) | 0.47 |
Tumor Necrosis Factor-α, pg/mL | 0.40 (−1.36, 2.17) | 0.65 | −0.34 (−1.74, 1.07) | 0.64 |
Adiponectin, ug/mL | 0.23 (−0.10, 0.56) | 0.17 | 0.04 (−0.22, 0.30) | 0.78 |
Leptin, mg/mL | 0.04 (−0.20, 0.28) | 0.75 | 0.16 (−0.03, 0.35) | 0.10 |
In a multivariate linear regression model
Prevalent hypertension is defined as hypertension defined as physician diagnosis of high blood pressure, use of anti-hypertensive medications, systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg; prevalent diabetes defined as physician diagnosis, fasting plasma glucose > 126 mg/dL, use of diabetes medication (pill or insulin)