(a) Sholl analysis of somatosensory cortex layer V pyramidal neurons in P30 WT (n=40 neurons from 4 animals) and Mecp2T158A/y mice (n=34 neurons from 4 animals) show no change dendritic complexity in Mecp2T158A/y mice relative to WT. Two-way ANOVA, p>0.05. Bars represent mean ± sem.
(b) Sholl analysis of somatosensory cortex layer V pyramidal neurons in P90 WT (n=36 neurons from 4 mice) and Mecp2T158A/y mice (n=39 neurons from 4 mice) show reduced dendritic complexity in Mecp2T158A/y mice relative to WT specifically in the basal dendritic arbor. Two-way ANOVA with Bonferroni correction, p<0.0001 (interaction); **p<0.01.