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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Neurobiol Dis. 2013 May 6;58:3–12. doi: 10.1016/j.nbd.2013.04.020

Figure 4. Dendritic complexity in hippocampus CA1 of Mecp2T158A/y mice.

Figure 4

(a) Sholl analysis of hippocampal CA1 pyramidal neurons in P30 WT (27 neurons from 5 mice) and Mecp2T158A/y mice (n=33 neurons from 5 mice) show no change dendritic complexity in Mecp2T158A/y mice relative to WT. Two-way ANOVA, p>0.05. Bars represent mean ± sem.

(b) Sholl analysis of hippocampal CA1 pyramidal neurons in P90 WT (n=32 neurons from 5 mice) and Mecp2T158A/y mice (n=40 neurons from 5 mice) show altered dendritic complexity in Mecp2T158A/y mice relative to WT specifically in the basal dendritic arbor. Two-way ANOVA with Bonferroni correction, p<0.0001 (interaction); *p<0.05, **p<0.01.

(c) Sholl analysis of basal dendritic complexity of hippocampal CA1 pyramidal neurons in P90 WT and Mecp2T158A/y mice show no difference in peak number of crossings in Mecp2T158A/y mice relative to WT.