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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Neurobiol Dis. 2013 May 6;58:3–12. doi: 10.1016/j.nbd.2013.04.020

Figure 5. Soma size is regulated throughout development by MeCP2 function.

Figure 5

(a) Somatosensory cortex layer V pyramidal neuron soma size is reduced in Mecp2−/y mice relative to WT at both P30 (WT: n=124 neurons from 4 mice; Mecp2−/y: n=103 neurons from 4 mice) and P60 (WT: n=126 neurons from 4 mice; Mecp2−/y: n=104 neurons from 4 mice). **p<0.01, unpaired two-tailed Student t-test with Bonferroni correction. Bars represent mean ± SEM.

(b) Somatosensory cortex layer V pyramidal neuron soma size is reduced in Mecp2T158A/y mice relative to WT at both P30 (WT: n=115 neurons from 4 mice; Mecp2T158A/y: n=121 neurons from 4 mice) and P90 (WT: n=81 neurons from 4 mice; Mecp2T158A/y: n=106 neurons from 4 mice). **p<0.01, unpaired two-tailed Student t-test with Bonferroni correction.