(a) Sholl analysis of somatosensory cortex layer V pyramidal neurons in P30 WT (n=16 neurons from 2 mice) and Mecp2Tg1 mice (n=19 neurons from 2 mice) show no change dendritic complexity in Mecp2Tg1 mice relative to WT. Two-way ANOVA, p>0.05. Bars represent mean ± sem.
(b) Sholl analysis of somatosensory cortex layer V pyramidal neurons in P140 WT (n=23 neurons from 2 mice) and Mecp2Tg1 mice (n=23 neurons from 2 mice) show no change dendritic complexity in Mecp2Tg1 mice relative to WT. Two-way ANOVA, p>0.05.
(c) Somatosensory cortex layer V pyramidal neuron soma size is not affected in Mecp2Tg1mice relative to WT at both P30 (WT: n=101 neurons from 2 mice; Mecp2Tg1: n=110 neurons from 2 mice) and P140 (P140; n=110 neurons from 2 mice; Mecp2Tg1: n=113 neurons from 2 mice). p>0.05, unpaired two-tailed Student t-test.