Table 3.
Adjusted Odds Ratios of the risk factors a in metabolically benign overweight/obese vs. metabolically benign normal weight body size phenotypes.b
| Model 1c | Model 2d | |||
|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |
| Top Tertile of Epicardial Fat Volume | ||||
| MBNW | 1.00 | (reference) | 1.00 | (reference) |
| MBO | 5.17 | 3.22 – 8.29 | 4.99 | 3.04 – 8.18 |
| Top Tertile of Pericardial Fat Volume | ||||
| MBNW | 1.00 | (reference) | 1.00 | (reference) |
| MBO | 9.27 | 5.52 – 15.56 | 8.31 | 4.90 – 14.08 |
| Bottom Tertile of Hepatic Fat Attenuation Score | ||||
| MBNW | 1.00 | (reference) | 1.00 | (reference) |
| MBO | 2.72 | 1.77 – 4.19 | 2.53 | 1.62 – 3.94 |
| Top Tertile of Leptin | ||||
| MBNW | 1.00 | (reference) | 1.00 | (reference) |
| MBO | 11.07 | 6.03 – 20.32 | 9.74 | 5.19 – 18.28 |
| Bottom Tertile of Soluble Leptin Receptor | ||||
| MBNW | 1.00 | (reference) | 1.00 | (reference) |
| MBO | 4.28 | 2.69 – 6.83 | 3.49 | 2.14 – 5.70 |
| Bottom Tertile of HMW Adiponectin | ||||
| MBNW | 1.00 | (reference) | 1.00 | (reference) |
| MBO | 2.51 | 1.60–3.94 | 2.27 | 1.42 – 2.60 |
MBNW – Metabolically Benign Normal Weight Phenotype
MBO – Metabolically Benign Obese Phenotype
a
Risk factors include: top tertile of epicardial fat, pericardial fat, and leptin, and bottom tertile of hepatic attenuation score, soluble leptin receptor and HMW adiponectin
b
Metabolically benign phenotype definition: ≤1 of: elevated blood pressure (≥130/85 mmHg), elevated TG (≥150 mg/dL), elevated fasting glucose (≥100 mg/dL), low HDL cholesterol (<50 mg/dL).
c
Model 1: adjusted for age, race, site of recruitment, education, physical activity, smoking, and alcohol
d
Model 2: Model 1 + waist circumference