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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Eur Neuropsychopharmacol. 2012 Aug 24;23(8):960–971. doi: 10.1016/j.euroneuro.2012.08.005

Figure 5.

Figure 5

Dopamine transporter (DAT) Immunohistochemistry: Effect of SN79 pretreatment on methamphetamine (METH)-induced decrease in striatal DAT levels. Male, Swiss Webster mice (N = 4/group) were pretreated with saline (Sal) or SN79 (SN, 3 mg/kg, i.p.). After 15 min, the mice were then treated with Sal or METH (5 mg/kg, i.p.). This treatment schedule was repeated four times at 2 h intervals. One week later, the brains were removed and stained for DAT immunoreactivity. Average optical density readings (mean ± SEM) are shown. ***P<0.001 vs. saline, ###P<0001 vs. METH.