Table 2.
Treatment-related toxicities
| Toxicity | Grade 3: Number (%) |
Grade 4: Number (%) |
|---|---|---|
| Neutropenia | 12 (39) | 8 (26) |
| Leukopenia | 10 (32) | 3 (10) |
| Diarrhea | 10 (32) | 0 |
| Lymphopenia | 8 (26) | 0 |
| Infection | 6 (19) | 0 |
| Pain | 4 (13) | 0 |
| Fatigue | 4 (13) | 0 |
| Electrolyte abnormalities |
4 (13)a | 0 |
| Pulmonary toxicity | 2 (6)b | 0 |
| Neuropathy | 2 (6) | 0 |
| Skin toxicity | 2 (6) | 0 |
| Nausea/emesis | 2 (6) | 0 |
| Elevated ALT | 2 (6) | 0 |
| Prolonged PTT | 2 (6) | 0 |
| Mucositis | 1 (3) | 0 |
| Cardiac toxicity | 0 | 0 |
| Anemia | 0 | 0 |
| Thrombocytopenia | 0 | 0 |
| Other | 3 (10)c | 0 |
PTT partial thromboplastin time. ALT alanine transaminase
a
Hyponatremia, hypokalemia, hypophosphatemia
b
Dyspnea
c
Anorexia, dehydration