Table 1. Genes in polyribosome fractions upregulated > 2-fold in DTT-treated U87MG cells over untreated cells.
| UniGene ID | Fold Change | Gene Name |
|---|---|---|
| Hs. 250666 | 6.108 | Transcription factor HES-1 (Hairy and enhancer of split 1) |
| Hs. 632460 | 4.045 | Selenium binding protein 1 |
| Hs. 694727 | 3.882 | Serpin-F1 /PEDF/EPC-1 (pigment epithelium-derived factor) |
| Hs. 390594 | 3.638 | Cystine/glutamate transporter, solute carrier family 7 member 11 |
| Hs. 433668 | 3.473 | Transmembrane protein 50B (HCV p7-trans-regulated protein 3) |
| Hs. 436446 | 3.417 | ARMET protein (arginine-rich, mutated in early stage tumors) |
| Hs. 533336 | 3.221 | BMP and activin membrane-bound inhibitor homolog (BAMBI) |
| Hs. 303116 | 3.136 | Stromal cell-derived factor 2-like (SDF2 like protein 1) |
| Hs. 605502 | 3.132 | BiP (glucose regulated protein 78 kDa) |
| Hs. 336681 | 3.007 | Zinc finger protein, X-linked |
| Hs. 616962 | 2.877 | Growth differentiation factor 15 / Macrophage Inhibitory Cytokine-1 |
| Hs. 504609 | 2.587 | Inhibitor of DNA binding 1, dominant negative HLH protein |
| Hs. 166463 | 2.564 | Heterogeneous nuclear ribonucleoprotein U |
| Hs. 372579 | 2.436 | Mental retardation X-linked 85/Vasorin/SLIT2 |
| Hs. 1524 | 2.388 | Tumor necrosis factor (ligand) superfamily member 9 |
| Hs. 408542 | 2.341 | Sugen kinase 493/ hypothetical protein BC007901 |
| Hs. 567352 | 2.301 | Thioredoxin reductase 1 |
| Hs. 146393 | 2.210 | HERP (homocysteine-responsive ER-resident ubiquitin-like protein |
| Hs. 516157 | 2.193 | Methionine adenosyltransferase II alpha |
| Hs. 529353 | 2.146 | Acyl-CoA synthetase short-chain family member 1 |
| Hs. 652291 | 2.130 | CD24 molecule |
| Hs. 517581 | 2.122 | Heme oxygenase 1 (EC 1.1499.3) |
| Hs. 31210 | 2.095 | B-cell lymphoma 3-encoded protein (Bcl-3 protein) |
| Hs. 484950 | 2.069 | Histone 1 H2ac |
| Hs. 516862 | 2.053 | Tribbles homolog 3 |
| Hs. 8417 | 2.041 | Calcium/calmodulin-dependent protein kinase kinase 1 |
| Hs. 298990 | 2.037 | Probable global transcription activator SNF2L2/SMARCA2 |
| Hs. 523835 | 2.033 | Cyclin-dependent kinase 2 associated protein 2 (DOC 1R) |
| Hs. 370771 | 2.028 | Cyclin-dependent kinase inhibitor 1 (p21) (CDK-interacting protein 1) |
| Hs. 432132 | 2.020 | G0/G1switch 2 |
Of the 1085 genes significantly over-expressed in solid U87 tumors compared to U87 tissue culture cells, these 30 genes were expressed > 2-fold in DTT-treated U87 cells compared to untreated U87 cells. UniGene Human (Homo sapien, “Hs”) identifiers are listed at left.