Table 2.
Characteristics of DUSP1 sequence variations identified by direct sequencing in 25 severely obese individuals.
| rs number | Other designationa | Region | MAF | HWE P value |
|---|---|---|---|---|
| rs322381 | c. −1534C>T | Promoter | 0.02 | 1.00 |
| — | c. −1430G>A | Promoter | 0.38 | 0.006 |
| rs13184134 | c. −1411C>T | Promoter | 0.14 | 1.00 |
| rs322382 | c. −997A>G | Promoter | 0.30 | 1.00 |
| rs881150 | c. −950A>T | Promoter | 0.26 | 0.96 |
| — | c. −648G>T | Promoter | 0.02 | 1.00 |
| rs2070996 | c. −545C>T | Promoter | 0.16 | 1.00 |
| rs28372789 | c. −333delA | Promoter | 0.46 | 0.06 |
| — | c. 106A>C; p.Asn36His | Exon 1 | 0.02 | 1.0 |
| — | c. 120C>T; p.Ile40Ile | Exon 1 | 0.02 | 1.0 |
| rs200878863 | c. 158G>T; p.Arg53Leu | Exon 1 | 0.02 | 1.0 |
| rs201026723 | c. 180G>C; p.Met60Ile | Exon 1 | 0.04 | 1.0 |
| rs34507926 | c. 367+8C>G | Intron 1 | 0.04 | 1.0 |
| rs35084382 | c. 513+125A>G | Intron 2 | 0.02 | 1.0 |
| rs7702178 | c. 513+167A>G | Intron 2 | 0.16 | 1.0 |
| rs2431663 | c. 600C>A; p.Ile200Ile | Exon 3 | 0.02 | 1.0 |