Table 1.
Summary of cases of vitiligo following radiotherapy reported in the literature.
| Sr. no. | Author | Number of cases | Cancer for which radiation was given | Preexisting vitiligo | Chemotherapy | Time to hypopigmentation after completion of radiotherapy (months) |
Reference |
|---|---|---|---|---|---|---|---|
| (1) | Pajonk et al. | 1 | Hodgkin's disease | Yes | N/A | N/A | [6] |
| (2) | Polat et al. | 1 | Nasopharyngeal carcinoma | No | Cisplatin (concurrent) | 2 | [7] |
| (3) | Levine and Ribeiro | 2 | Breast cancer | Yes | N/A | N/A | [8] |
| (4) | Koo et al. | 2 | Breast cancer | Yes | Yes (details N/A) | 7 | [9] |
| Breast cancer | Yes | Yes (details N/A) | 8 | ||||
| (5) | Weitzen et al. | 1 | Breast cancer | Yes | Yes (Anthracycline based) | 2 | [10] |
| (6) | Roth | 1 | Melanoma | N/A | N/A | N/A | [11] |
| (7) | Munshi et al. | 1 | Breast cancer | Yes | Yes | 6 | [4] |
| (8) | Kim et al. | 1 | Thymoma | No | No | 3 | [12] |
| (9) | The authors | 1 | Breast cancer | No | Yes | 9 | N/A |
| Total cases including authors' single case | 11 | Breast cancer: 7 Other cancers: 4 |
Preexisting vitiligo: 7 None: 4 |
Chemo-experienced: 7 Not available: 4 |
Median time to develop vitiligo at radiation site: 6 months (n = 7) | ||