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Summary of sequence and structural similarities between the homology models of dengue polymerase (novel and conventional approaches) and the RdRp known structures (RCSB codes in parenthesis) used as templates.
| Template | Sequence comparison | RMSd (Å) | ||||
|---|---|---|---|---|---|---|
| Number of equivalent amino acids | Identity (%) | Similarity (%) | Number of atoms | Novel | Conventional | |
| HCV RdRp (1NB7) | 351 | 18 | 34 | 139 (C α) | 1.19 | 3.57 |
| BVDV RdRp (1S48) | 172 | 18 | 31 | 65 (C α) | 1.04 | 3.04 |
