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. Author manuscript; available in PMC: 2013 Aug 21.
Published in final edited form as: JAMA. 2013 May 1;309(17):1803–1809. doi: 10.1001/jama.2013.3710

Table 2.

Reasons for Switching Nonnucleoside Reverse Transcriptase Inhibitors

No. (%) of Total Cohorta
Switched from efavirenz to nevirapine (n = 26)
 Puberty 13 (3.1)

 Gynecomastia 7 (1.7)

 Neuropsychiatric effects 4 (1.0)

 Out of stock 2 (0.5)

Switched from nevirapine to efavirenz (n = 13)
 Dermatologic reaction 5 (1.3)b

 Regimen simplification 4 (1.0)

 Hepatotoxic effects 3 (0.8)b

 Emesis 1 (0.3)

 Not documented 1 (0.3)
a

There were 421 patients who started taking efavirenz and 383 who started taking nevirapine.

b

One patient had 2 reasons for the treatment switch.