. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Calcif Tissue Int. 2013 May 25;93(3):211–221. doi: 10.1007/s00223-013-9744-4

Table 3.

Cortical bone morphology of left (contralateral) and right (“loaded”) tibia from C57BL/6 and BALB/c mice over 6 weeks

Parameter	Strain	Time [week]	AC		WashU		Cornell/HSS
Parameter	Strain	Time [week]	Left	Right	Left	Right	Left	Right
Cortical Bone Volume [mm³]^G, ^T	C57BL/6	0	0.60±0.05	0.58±0.06	0.60±0.03	0.60±0.03	0.61±0.05	0.59±0.03
		3	0.60±0.05	0.58±0.03	0.61±0.03	0.62±0.02	0.59±0.04	0.67±0.04^*,^a,^b,^†
		6	0.62±0.05	0.60±0.05	0.62±0.02	0.71±0.02^*,^a,^†,^‡	0.62±0.03	0.70±0.04^*,^a,^†
	BALB/c	0	0.64±0.04	0.62±0.04^*	0.64±0.04	0.62±0.03^*	0.65±0.03	0.64±0.03
		3	0.62±0.05	0.60±0.06^*	0.64±0.03	0.67±0.03^*,^†	0.62±0.04	0.74±0.10^*,^a,^b,^†
		6	0.63±0.06	0.62±0.06	0.62±0.04	0.71±0.03^*,^a,^†,^‡	0.62±0.04	0.77±0.07^*,^a,^†
Tt.Ar [mm²]^G, ^T	C57BL/6	0	1.42±0.15	1.40±0.19	1.43±0.15	1.47±0.14	1.50±0.21	1.45±0.16
		3	1.31±0.10	1.30±0.09	1.39±0.08	1.52±0.06^*,^a,^†	1.37±0.12	1.58±0.09^*,^a,^†
		6	1.32±0.11	1.29±0.12	1.36±0.07	1.43±0.09^*,^a	1.34±0.11	1.52±0.09^*,^a,^b,^†
	BALB/c	0	1.40±0.11	1.36±0.12	1.40±0.14	1.37±0.11	1.43±0.08	1.43±0.06^a
		3	1.35±0.08	1.33±0.11	1.39±0.12	1.51±0.14^*,^a,^†	1.37±0.17	1.58±0.12^*,^a,^b,^†
		6	1.29±0.12	1.34±0.18	1.28±0.07	1.46±0.07^*,^†,^‡	1.33±0.11	1.58±0.11^*,^a,^†
M.Ar [mm²]^G, ^T	C57BL/6	0	0.70±0.10	0.70±0.15	0.72±0.13	0.76±0.12	0.78±0.18	0.75±0.15
		3	0.61±0.04	0.62±0.10	0.65±0.09	0.76±0.14^*,^a	0.65±0.13	0.77±0.08^*,^a,^†
		6	0.55±0.04	0.55±0.05	0.59±0.09	0.63±0.06^*,^a	0.61±0.09	0.71±0.08^*,^a,^b,^†
	BALB/c	0	0.61±0.08	0.61±0.08	0.60±0.09	0.59±0.09	0.62±0.05	0.64±0.05
		3	0.55±0.06	0.55±0.05	0.57±0.05	0.60±0.10	0.57±0.06	0.59±0.17
		6	0.51±0.06	0.56±0.11	0.51±0.05	0.56±0.08	0.56±0.07	0.60±0.06
Ct.Th [mm]^G, ^T, ^M	C57BL/6	0	0.16±0.01	0.16±0.01	0.16±0.01	0.15±0.01^*	0.16±0.01	0.15±0.01
		3	0.17±0.01	0.17±0.01	0.17±0.01	0.16±0.01	0.17±0.01	0.17±0.02^†
		6	0.18±0.01	0.18±0.01	0.17±0.01	0.20±0.01^*,^a,^†,^‡	0.18±0.01	0.19±0.01^*,^a,^b,^†
	BALB/c	0	0.20±0.01	0.19±0.01^*	0.20±0.01	0.19±0.01	0.20±0.01	0.19±0.01^*
		3	0.20±0.01	0.19±0.01^*	0.19±0.01	0.20±0.02	0.19±0.01	0.21±0.02a
		6	0.20±0.01	0.19±0.01^*	0.20±0.01	0.22±0.02^*,^a,^†,^‡	0.19±0.01	0.23±0.02^*,^a,^†,^#

Data are presented as mean±SD.

: Difference between left (contralateral) and right (“loaded”) tibia;

: main effect of group,

: relative change (Loaded vs Contralateral, %) different from AC of same mouse strain and time,

: relative change different from WashU of same mouse strain and time;

: main effect of time,

^†

: relative change different from 0 week of same group and mouse,

^‡

: relative change of 6 week different from 3 week of same group and mouse,

: main effect of mouse strain,

: relative change different from C57BL/6 of same group and time; p<0.05.