Table 4.
Mechanical properties of left (contralateral) and right (“loaded”) tibia from C57BL/6 and BALB/c mice at 6 weeks
Parameter | Strain | AC | WashU | Cornell/HSS | |||
---|---|---|---|---|---|---|---|
Left | Right | Left | Right | Left | Right | ||
Ultimate Force [N]G | C57BL/6 | 24.5±2.8 | 26.6±3.2 | 26.5±3.6 | 28.3±2.4 | 25.4±1.7 | 29.1±2.8* |
BALB/c | 21.1±2.7 | 22.1±2.7 | 23.6±3.4 | 25.9±2.7 | 23.8±1.8 | 28.4±2.5*,a | |
Ultimate Displacement [mm]G | C57BL/6 | 0.7±0.3 | 0.7±0.1 | 0.7±0.2 | 1.0±0.3*,a | 0.6±0.1 | 0.9±0.1*,a |
BALB/c | 0.6±0.1 | 0.6±0.1 | 0.7±0.1 | 1.0±0.2*,a | 0.7±0.1 | 1.1±0.2*,a | |
Stiffness [N·mm−1]G | C57BL/6 | 62±18 | 68±7 | 69±20 | 53±10 | 67±7 | 55±8* |
BALB/c | 49±8 | 56±13 | 54±9 | 49±10 | 52±6 | 53±8 | |
Energy-to-Fracture [N·mm]G | C57BL/6 | 7.5±0.6 | 8.2±2.3 | 8.8±1.7 | 10.7±2.2 | 7.3±1.2 | 12.1±2.7*,a |
BALB/c | 6.3±0.8 | 6.8±1.4 | 7.4±1.0 | 10.0±1.3*,a | 7.9±1.2c | 10.9±1.7*,a |
Data are presented as mean±SD.
: Difference between left (contralateral) and right (“loaded”) tibia;
: main effect of group,
: relative change (Loaded vs Contralateral, %) different from AC of same mouse strain and time,
: absolute value of contralateral outcome different from contralateral of AC from same mouse; p<0.05.