Table 1.

Summary of leukodystrophy patient numbers and costs from PHIS database of U.S. children’s hospitals. Results are compared to the total for all PHIS patients, and to the average PHIS patient. Years 2004–2010, PHIS database total n= 2,272,591 patients; total cost $60,166,647,000.

Category	Number (%)
Unique leukodystrophy patients	3,143 (0.09%)
Leukodystrophy patients/10,000 total patients	9.02
Leukodystrophy patient admissions	13,554 (0.38%)
Leukodystrophy admissions/10,000 patient admissions	38.9
Leukodystrophy patient costs	$411,374,000 (0.68%)
Average leukodystrophy patient cost	$130,886
Average PHIS patient cost	$26,475
Cost ratio (and range) of leukodystrophy:average patient	4.9 (2.2 – 20.3)
Costs ratio per admission (and range) of leukodystrophy:average	1.8 (1.0–4.9)
Average leukodystrophy patient admissions	4.3
Average PHIS patient admissions	1.5
Admissions ratio (and range) of leukodystrophy:average patient	2.9 (2.0 – 5.4)