Figure 5.

The results of ELISA analysis based on the control index for total and acetylated P53 protein generated in MCF-7 and MRC-5 cells were treated with and without CTB at different times. Cells were treated with 85.43 μmol/L of CTB for 0, 24, 48 and 72 hours. Values are mean + SE of triplicate experiments. (a) *P<0.001 vs. all other groups in different time. **P< 0.05 vs. total P53 in MRC-5 with Salermide treatment at 72 hours. (b) *P< 0.001 vs. all other groups in different time. **P< 0.05 vs. total P53 in MRC-5 without CTB treatment and with CTB treatment at time 48 and 72 hours. No significant difference was shown in total and acetylated P53 content of other groups