Table 1.
AHR Protein Expression in Tumors
Tissue (References) | AHR protein expression |
---|---|
Pancreatic (Koliopanos et al., 2002) | 14/15 (tumors, m to h, cytosolic) |
9/15 (nontumors, f) | |
Prostate (Gluschnaider et al., 2010) | Tumors (h, cytosolic and nuclear) |
Nontumors (w-nd, cytosolic > nuclear) | |
Urinary tract (Ishida et al., 2010) | Tumors (h, % nuclear staining increased with increasing tumor grade) |
Nontumor (w, cytosolic and nuclear) | |
Lung (Portal-Nunez et al., 2012) | Adenocarcinomas (h, 56%) |
Bronchioloalveolar carcinomas (h, 47%) | |
Bronchiolar epithelium (h, 11%) | |
Lung (Lin et al., 2003) | Tumors (h, 59/91; l, 32/91) |
Nontumors (h, 7/31; l, 24/31) | |
Esophagus (Zhang et al., 2012a) | Tumors/nontumors = 2.2/1 in protein expression |
Pituitary (Jaffrain-Rea et al., 2009) | Tumors/nontumors: Weak staining, primarily cytosolic |
Gliomas (Gramatzki et al., 2009) | Expression in tumor and nontumor tissues (23 autopsies) |
WHO grade II astrocytomas > grade III anaplastic astrocytomas > grade IV glioblastomas (mean total AHR) | |
Grade IV glioblastomas > grade III anaplastic astrocytomas ≅ grade II astrocytomas (nuclear AHR protein) |
Note. m to h, medium to high; f, faint; w-nd, weak to nondetectable; w, weak.