Table 3.

Pathway Analysis of Differentially Expressed Genes in BPA-Treated Mice

Category	p Value
Gene set enrichment analysis
Innate immune response	0.0003
Translation	0.0009
Complement activation	0.006
Carbohydrate metabolic process	0.021
Antiapoptosis	0.033
Negative regulation of cell proliferation	0.039
Spermatid development	0.049
Pathway	p Value
Subnetworks enrichment analysis
Expression targets of IL1 family	0.010
Expression targets of TGFA	0.011
Expression targets of IL1A	0.021
Expression targets of CEBPA	0.041
Expression targets of HIF1A	0.043

Note. Gene ontology and subnetwork enrichment analysis were performed for differentially expressed genes using the Ariadne Pathway Studios program as detailed in the Materials and Methods section. p Values < 0.05 were considered significant.