Plasma cholesterol (A), plasma triglycerides (B), cholesterol (C) and triglycerides (D) levels in plasma FPLC fractions at 12 week and 24 weeks of diet in Tlr4−/−Ldlr−/− mice fed DD (black bars and solid circle lines) and chow (grey bars and solid triangle lines), Ldlr−/− control mice fed DD (hatched bars and open circle dash lines) and chow (open bars and open triangle dash lines);(n=10–15, *P<0.05, **P<0.01 vs DD or chow groups).