Plasma fasting glucose (A) and insulin levels (B), glucose tolerance tests (C–D), and insulin tolerance tests (E–F); (n=10–15, *P<0.05, **P<0.01 vs DD or chow groups). Tlr4−/−Ldlr−/− mice fed DD (black bars and solid circle lines) and chow (grey bars and solid triangle lines), Ldlr−/− control mice fed DD (hatched bars and open circle dash lines) and chow (open bars and open triangle dash lines).