FIGURE 4.

Effects of IH on renal antioxidants and renal lipid peroxidation. Renal tissue from FVB mouse exposed to intermittent air (C) or IH were subject to Western blotting assay for the expression of Nrf2 (A), HO-1 (B), MT (C), NQO-1 (D), and SOD1 (E). Concentration of renal lipid peroxides (F) was determined by TBA assay, which measures the amount of thiobarbituric acid reactivity with malondialdehyde (MDA) formed during the acid hydrolysis of lipid peroxide compound. Lipid peroxide level was expressed in terms of nanomoles MDA per gram wet weight. Data are presented as mean ± SD (n = 3 – 8). *, p < 0.05 vs corresponding controls.