Table 2. Summary of treatment toxicity.
Toxicity Cohort1 | Grade 2 | Grade 3 | Grade 4 | |||
---|---|---|---|---|---|---|
A | B | A | B | A | B | |
| ||||||
Anemia | 2 (6) | 1 (3) | 1 (3) | |||
Anorexia | 2 (6) | 2 (6) | ||||
Creatinine increase | 1 (3) | |||||
Diarrhea | 5 (16) | 3 (9) | 1 (3) | 1 (3) | 1 (3) | |
Edema | 2 (6) | |||||
Fatigue | 12 (38) | 13 (41) | 1 (3) | |||
Infection | 4 (12) | 3 (9) | 1 (3) | |||
Mucositis | 1 (3) | |||||
Nausea | 10 (31) | 5 (16) | 1 (3) | 1 (3) | ||
Neutropenia | 2 (6) | 2 (6) | 3 (9) | 1 (3) | 1 (3) | |
Rash | 5 (16) | 2 (6) | ||||
Thrombocytopenia | 2 (6) | |||||
Transaminase elevation | 1 (3) | |||||
Weight loss | 1 (3) |
numbers in parentheses indicate percentage of treated patients
A: astrocytoma cohort; B: oligodendroglioma cohort