Table 1.
Baseline Characteristics of Women and Men According to Ankle-Brachial Index (ABI), MESA (2000–2002)
| Women (N=2803) | Men (N=2558) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ABI | ABI | |||||||||
| Definite PAD (<0.90) |
Borderline ABI (0.90-<1.00) |
Low-normal ABI (1.00-<1.10) |
Normal ABI (1.10-<1.40) |
P trend | Definite PAD (<0.90) |
Borderline ABI (0.90-<1.00) |
Low-normal ABI (1.00-<1.10) |
Normal ABI (1.10-<1.40) |
P trend | |
| N | 81 | 270 | 1047 | 1405 | 73 | 105 | 552 | 1828 | ||
| Age (years) | 70.2 (9.9) | 64.2 (10.2) | 62.2 (10.0) | 59.6 (9.6) | <0.001 | 69.5 (9.1) | 66.2 (10.1) | 62.6 (10.2) | 60.7 (9.8) | <0.001 |
| Body mass index (kg/m2) | 28.4 (5.7) | 28.3 (5.9) | 28.1 (5.8) | 29.0 (6.3) | <0.001 | 27.2 (3.9) | 28.1 (4.8) | 27.2 (4.3) | 28.0 (4.3) | <0.001 |
| Smoking (%) | ||||||||||
| Current | 14.8 | 16.7 | 10.4 | 10.2 | 0.011 | 27.4 | 19.0 | 18.1 | 11.3 | <0.001 |
| Never | 51.8 | 53.3 | 60.1 | 61.7 | 0.006 | 20.5 | 26.7 | 36.6 | 44.6 | <0.001 |
| Blood pressure (mmHg) | ||||||||||
| Systolic | 141.5 (28.7) | 133.2 (23.0) | 128.8 (23.3) | 120.7 (20.2) | <0.001 | 136.6 (23.2) | 132.5 (19.7) | 127.0 (19.4) | 124.1 (18.0) | <0.001 |
| Diastolic | 70.5 (12.1) | 70.3 (11.1) | 69.6 (10.3) | 68.0 (9.6) | <0.001 | 74.2 (10.3) | 75.4 (9.1) | 75.4 (9.5) | 75.1 (9.1) | 0.199 |
| Medication Use (%) | ||||||||||
| Blood Pressure | 54.3 | 45.2 | 39.2 | 31.2 | <0.001 | 58.9 | 45.7 | 36.6 | 32.5 | <0.001 |
| Statin | 30.9 | 19.3 | 14.5 | 12.7 | <0.001 | 20.5 | 20.9 | 14.3 | 13.8 | 0.030 |
| Diabetes (%) | 30.9 | 8.1 | 9.9 | 9.7 | 0.005 | 19.2 | 14.3 | 12.3 | 11.9 | 0.106 |
| Cholesterol (mg/dL) | ||||||||||
| Total | 203.0 (32.8) | 197.3 (35.5) | 200.1 (34.2) | 199.1 (34.5) | 0.274 | 187.6 (35.4) | 191.1 (35.0) | 189.2 (38.0) | 187.6 (33.4) | 0.082 |
| HDL | 53.0 (14.1) | 56.5 (15.2) | 57.0 (15.9) | 56.4 (14.7) | 0.747 | 44.4 (10.9) | 46.3 (12.8) | 45.3 (12.0) | 44.9 (11.4) | 0.605 |
| Total/HDL ratio | 4.1 (1.3) | 3.7 (1.1) | 3.7 (1.1) | 3.7 (1.1) | 0.120 | 4.4 (1.2) | 4.4 (1.2) | 4.4 (1.5) | 4.4 (1.2) | 0.265 |
| GFR | 73.0 (20.6) | 79.1 (17.0) | 79.9 (17.0) | 81.0 (17.1) | 0.001 | 82.3 (18.6) | 81.4 (19.7) | 83.7 (18.1) | 82.0 (16.4) | 0.876 |
*
Data are expressed as mean (SD) unless otherwiseindicated.