TABLE II.
Comparison of HR-pQCT-Derived Volumetric Densities and Bone Microarchitecture Measures in Fracture and Control Groups
Distal End of Radius |
Distal End of Tibia |
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Variable | Fracture* (N = 40) | Controls* (N = 80) | P Value | Fracture* (N = 40) | Controls* (N = 80) | P Value |
Total density (mg HA/cm3) | 304 ± 57 | 327 ± 51 | 0.026 | 293 ± 47 | 328 ± 52 | 0.001 |
Trabecular density (mg HA/cm3) | 146 ± 32 | 172 ± 33 | <0.001 | 156 ± 32 | 182 ± 37 | <0.001 |
Cortical bone density (mg HA/cm3) | 866 ± 50 | 866 ± 49 | 0.983 | 894 ± 39 | 902 ± 33 | 0.22 |
Total area (mm2) | 263 ± 42 | 257 ± 43 | 0.48 | 668 ± 122 | 651 ± 110 | 0.44 |
Trabecular area (mm2) | 212 ± 42 | 205 ± 43 | 0.46 | 551 ± 123 | 525 ± 112 | 0.24 |
Cortical area (mm2) | 51 ± 10 | 52 ± 10 | 0.88 | 117 ± 16 | 126 ± 20 | 0.014 |
Trabecular thickness (mm) | 0.06 ± 0.01 | 0.07 ± 0.01 | 0.002 | 0.07 ± 0.01 | 0.08 ± 0.01 | 0.005 |
Trabecular number (mm−1) | 1.89 ± 0.36 | 2.02 ± 0.23 | 0.032 | 1.82 ± 0.34 | 1.93 ± 0.31 | 0.13 |
Trabecular separation (mm) | 0.49 ± 0.15 | 0.43 ± 0.06 | 0.014 | 0.50 ± 0.13 | 0.46 ± 0.09 | 0.037 |
Stand. dev. of trabecular separation (mm) | 0.22 ± 0.12 | 0.17 ± 0.03 | 0.032 | 0.24 ± 0.14 | 0.21 ± 0.06 | 0.068 |
Cortical thickness (mm) | 0.76 ± 0.15 | 0.77 ± 0.15 | 0.57 | 1.17 ± 0.19 | 1.28 ± 0.23 | 0.014 |
The values are given as the mean and the standard deviation.