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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Thromb Haemost. 2012 Nov 29;109(1):118–126. doi: 10.1160/TH12-04-0237

Figure 1. Effect of depleting the PP1c isoforms on 293 αIIbβ3 cell adhesion.

Figure 1

(A) Lysate from the control siRNA and PP1c depleted cells were immunoblotted with anti-PP1c pan antibody (recognizes all PP1c isoforms), anti-PP2Ac and anti-actin (loading). (B) Adhesion of 293 αIIbβ3 cells treated with either control or PP1c α, β or γ1 siRNAs to fibrinogen. Compared to control siRNA, the decreased adhesion of all PP1c isoform depleted cells were significant at ◆p<0.001, *p=0.002. n=4-7. (C) Adhesion of 293 αIIbβ3 cells treated with control or PP1c α, β or γ1 siRNAs to fibronectin. The adhesion difference between control and PP1c depleted cells from 3 experiments were not significant (P>0.05).