Table 1. PRISM patient data.
| Total | AD | ALS | MS | PD | Stroke | TBI | ||
| Sample size, n (%) | 5290 (100) | 1799 (34.0) | 125 (2.4) | 1215 (23.0) | 804 (15.2) | 757 (14.3) | 590 (11.2) | |
| Patient age, years, | Mean (SD) | 65.8 (17.8) | 79.2 (9.8) | 60.0 (12.8) | 48.8 (12.1) | 72.8 (10.5) | 68.3 (14.7) | 48.5 (16.5) |
| Age group, n (%) | ≥65 years | 3048 (57.6) | 1660 (92.3) | 54 (43.2) | 112 (9.2) | 639 (79.5) | 476 (62.9) | 107 (18.1) |
| ≥75 years | 2093 (39.6) | 1338 (74.4) | 15 (12.0) | 19 (1.6) | 392 (48.8) | 284 (37.5) | 45 (7.6) | |
| Patient gender, n (%) | Female | 3184 (60.2) | 1124 (62.5) | 47 (37.6) | 979 (80.6) | 333 (41.4) | 408 (53.9) | 293 (49.7) |
| Male | 2106 (39.8) | 675 (37.5) | 78 (62.4) | 236 (19.4) | 471 (58.6) | 349 (46.1) | 297 (50.3) | |
| Years since diagnosis | Sample size | (n = 2677) | (n = 656) | (n = 108) | (n = 785) | (n = 386) | (n = 395) | (n = 347) |
| Mean (SD) | 6.7 (8.1) | 3.7 (3.7) | 2.3 (3.2) | 9.9 (9.0) | 5.3 (6.5) | 4.6 (6.0) | 10.3 (11.5) | |
| Medication use,* n (%) | Any use | 2213 (41.8) | 864 (48.0) | 50 (40.0) | 459 (37.8) | 248 (30.8) | 296 (39.1) | 296 (50.2) |
| TCA | 689 (13.0) | 360 (20.0) | 1 (0.8) | 34 (2.8) | 75 (9.3) | 94 (12.4) | 125 (21.2) | |
| nonTCA | 1690 (31.9) | 592 (32.9) | 47 (37.6) | 414 (34.1) | 178 (22.1) | 235 (31.0) | 224 (38.0) | |
| Antipsychotic | 190 (3.6) | 85 (4.7) | 4 (3.2) | 31 (2.6) | 23 (2.9) | 18 (2.4) | 29 (4.9) | |
| Any 2 | 332 (6.3) | 165 (9.2) | 2 (1.6) | 18 (1.5) | 28 (3.5) | 47 (6.2) | 72 (12.2) | |
| Any 3 | 12 (0.2) | 4 (0.2) | 0 (0) | 1 (0.1) | 0 (0) | 2 (0.3) | 5 (0.8) |
*
Use of antidepressant or antipsychotic medication.
AD, Alzheimer’s disease; ALS, amyotrophic lateral sclerosis; MS, multiple sclerosis; nonTCA, antidepressant other than tricyclic antidepressant; PD, Parkinson’s disease; SD, standard deviation; TCA, tricyclic antidepressant; TBI, traumatic brain injury.