Table 3. Top 30 most significant genes that showed differential expression between control and methionine-rich treatment.
Gene | Name | log2 FC | FDR |
LAPTM5 | Lysosomal protein transmembrane 5 | −14.9 | 4.7×10−9 |
NKG7 | Natural killer cell group 7 sequence | −13.6 | 4.4×10−8 |
VIM | Vimentin | −13.8 | 1.8×10−7 |
TYROBP | TYRO protein tyrosine kinase binding protein | −13.2 | 3.2×10−6 |
IFI6 | Interferon, alpha-inducible protein 6 | −12.6 | 1.5×10−5 |
CUFF.2147.1 | Novel transcript unit | −8.2 | 1.5×10−5 |
LOC505451 | Olfactory receptor, family 1, subfamily J, member 2-like | −13.0 | 1.5×10−5 |
SLAMF7 | Signaling lymphocyte-activating molecule family 7 family member 7 | −10.4 | 3.5×10−5 |
LOC788199 | Olfactory receptor 6C74-like | −10.4 | 7.6×10−5 |
LCP1 | Lymphocyte cytosolic protein 1 (L-plastin) | −9.9 | 1.1×10−4 |
LOC100849660 | Uncharacterized | 11.9 | 2.2×10−4 |
BLA-DQB | MHC class II antigen | −11.1 | 2.2×10−4 |
SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | −11.5 | 3.4×10−4 |
NT5C3 | 5′-nucleotidase, cytosolic III | −11.5 | 3.5×10−4 |
LOC510193 | Apolipoprotein L, 3-like | 7.8 | 4.3×10−4 |
LOC100848815 | SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like | −11.4 | 4.3×10−4 |
CUFF.606.1 | Novel transcript unit | −5.6 | 4.3×10−4 |
LOC100850656 | Uncharacterized | −11.2 | 4.8×10−4 |
SLC11A1 | Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | −10.7 | 6.9×10−4 |
LOC100852347 | Beta-defensin 10-like | −11.2 | 7.3×10−4 |
LOC100297676 | C-type lectin domain family 2 member G-like | −6.8 | 9.2×10−4 |
BCL2A1 | BCL2-related protein A1 | −7.1 | 1.2×10−3 |
INSR | Insulin receptor | −5.1 | 1.3×10−3 |
NOVA1 | Neuro-oncological ventral antigen 1 | −10.6 | 1.5×10−3 |
TBX15 | T-box 15 | −11.2 | 2.2×10−3 |
TMEM200C | Transmembrane protein 200C | −6.6 | 2.2×10−3 |
GPNMB | Glycoprotein (transmembrane) nmb | −7.5 | 2.3×10−3 |
ARHGAP9 | Rho GTPase activating protein 9 | −5.7 | 2.7×10−3 |
EIF4E1B | Eukaryotic translation initiation factor 4E family member 1B | −11.3 | 3.1×10−3 |
LOC100295170 | Protein BEX2-like | −9.3 | 3.5×10−3 |
A negative log2 Fold Change (FC) value means that the gene showed higher expression in control treatment while a positive value means that the gene showed higher expression in methionine-rich treatment.