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. 2013 Aug 21;8(8):e71985. doi: 10.1371/journal.pone.0071985

Table 2. Association of the Pro12Ala polymorphism with type 2 diabetes mellitus.

Allele and genotype D2TM (%) Controls (%) Crude OR (95% CI), P Adjusted OR (95% CI), P
Pro/Pro 1060 (92.6) 1783 (89.1) 1.00 1.00
Pro/Ala and Ala/Ala 85 (7.4) 218 (10.9) 0.63 (0.48–0.81), 0.001 0.64 (0.49–0.83), 0.001
Pro 2201 (96.1) 3779 (94.4) 1.00 1.00
Ala 89 (3.9) 223 (5.6) 0.67 (0.52–0.86), 0.002 0.69 (0.54–0.88), 0.003

Adjusted for age, sex, BMI, hypertension, and family history of diabetes.

Abbreviations: CI, confidence interval; OR, odds ratio. The other abbreviations used see Table 1.