Table 4. Distribution of allele and genotype frequencies of the Pro12Ala polymorphism in study subjects stratified by BMI.
Subjects | PPAR genotypes | Crude OR (95% CI), P | Adjusted OR (95% CI), P | Ala allelic frequencies (%) | |
Pro/Pro (%) | Pro/Ala and Ala/Ala (%) | ||||
BMI 24 (n = 1772) | 1582 (89.3) | 190 (10.7) | 1.00 | 1.00 | 5.5 |
BMI 24–27.9 (n = 983) | 898 (91.4) | 85 (8.6) | 0.77 (0.58–1.00), 0.051 | 0.78 (0.59–1.02), 0.072 | 4.5 |
BMI ≥28 (n = 391) | 363 (92.8) | 28 (7.2) | 0.61 (0.40–0.93), 0.021 | 0.64 (0.42–0.96), 0.030 | 3.8 |