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. 2013 Aug 21;8(8):e72661. doi: 10.1371/journal.pone.0072661

Figure 3. Simplified schematic diagram highlighting the neural circuitry of the circadian-homeostatic-ultradian system and the functional neuroanatomical overlap with the thermoregulatory system.

Figure 3

Shaded regions denote sites of pathological damage in PD that have been demonstrated in previous neuropathological studies. KEYS: Ventrolateral preoptic nucleus (VLPO); ascending arousal system (AAS); preoptic nuclei of anterior hypothalamus (POAH); rostral ventrolateral medulla (RVLM); medullary autonomic region (AUTONOMIC); suprachiasmatic nuclei (SCN); pineal gland (PINEAL).