Table 3. Inhibitors used in the docking investigation.
CHEMBL ID of Inhibitor | IC50 (µM) | Binding Energy (kcal/mol) | |
LPL Inhibitors | CHEMBL339297* | 0.20 | −7.40 |
CHEMBL485946* | 1.40 | −6.10 | |
CHEMBL1952294 | 20.00 | −5.00 | |
CHEMBL1952314 | 500.00 | −4.10 | |
HL Inhibitors | CHEMBL339297* | 1.80 | −5.60 |
CHEMBL133897 | 15.00 | −5.90 | |
CHEMBL131588 | >500.00 | −3.70 | |
EL Inhibitors | CHEMBL467023 | 0.06 | −7.30 |
CHEMBL485946* | 0.10 | −8.00 | |
CHEMBL1952299 | 22.00 | −5.20 | |
CHEMBL1952301 | 50.00 | −4.40 |
Table with their CHEMBL ID, experimental IC50 value, and predicted binding energy are listed.
They are dual inhibitors.