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. 2013 Aug 21;8(8):e71827. doi: 10.1371/journal.pone.0071827

Table 4. Perceived barriers to advising adolescents aged 10–17 years for human papillomavirus (HPV) vaccination.

Extremely Likely or Somewhat Likely Extremely Unlikely, Somewhat unlikely, or Neutral
Parental refusal
Child too many vaccine 198 (56.1) 155 (43.9)
Safety concern 282 (78.6) 77 (21.4)
Not believe in vaccine 201 (56.8) 153 (43.2)
Less attentive to vaccine once child is >5 years 229 (62.6) 137 (37.4)
Parental reluctance to discuss sexuality/STD 254 (70.4) 107 (29.6)
Parental perception of singling out their child as at risk for STD 164 (44.9) 201 (55.1)
Parental concern of increasing risky behavior 149 (41.0) 214 (59.0)
Frequent changes of recommendation for immunization 155 (42.9) 206 (57.1)
Doctors’ reluctance to offer multiple vaccines 107 (30.1) 249 (69.9)
Doctors’ reluctance to discuss sexuality/STD 118 (32.3) 247 (67.7)
Difficult to get adolescents to show up for well visits/immunizations 207 (58.0) 150 (42.0)
Doctors’ reluctance since regular pap smear is still needed after vaccine 96 (26.4) 268 (73.6)
Doctors’ reluctance as vaccine’s protection is <100% 102 (28.2) 260 (71.8)
Too low parental awareness, time-consuming 187 (51.8) 174 (48.2)
Hard selling an expensive vaccine 234 (65.0) 126 (35.0)
Vaccination not related to the reasons of consultation 201 (55.7) 160 (44.3)
Not the doctors’ responsibility 65 (18.5) 286 (81.5)
Difficulty to initiate the conversation 125 (34.4) 238 (65.6)
Most adolescent patients not at risk for HPV infection 86 (24.2) 269 (75.8)
Most adolescent patients not at risk for cervical cancer 85 (23.5) 277 (76.5)

STD: Sexually Transmitted Disease.