Figure 7. Effects of NNMT downregulation on tumor growth in vivo.

The effect of NNMT silencing on the tumorigenic capacity was assessed by injection of mock and silenced cells into nude mice. Inoculation was performed in two groups (n = 10). Tumor size was measured weekly with caliper and the tumor volume was calculated. Data are expressed as mean of tumor volume of each group ± s.d. The differences between silenced group and control group were statistically significant (*, p = 0.0482).