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. 2013 Aug 21;8(8):e71594. doi: 10.1371/journal.pone.0071594

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(A) Structure of the foamy virus vectors. The UCOE631 promoter sequence from the human HNRPA2B1-CBX3 locus and transgenes were inserted into the FV vector. (B) Cell-surface expression of γc on ED40515(–) cells transduced with the FV-IL2RG vector. (C) STAT5 phosphorylation upon IL-2 stimulation. ED40515(–) cells, an ED40515(–)-derived transfectant with a γc gene, EDγ cells, and ED40515(–) cells transduced with the indicated vectors were stimulated with IL-2 for 30 min, and STAT5 phosphorylation in each cell line was detected by a STAT5 phosphospecific mAb.