Table 1.
Total cases | ER positive | ER negative | ER unknown | p value for heterogeneity | |||||
---|---|---|---|---|---|---|---|---|---|
Sample size | 62,549 | 45,571 | 12,016 | 4,962 | |||||
% Total cases | 100% | 72·9% | 19·2% | 7·9% | |||||
Mean age (SE) | 60.5 (0.05) | 60·9 (0·05) | 57·9 (0·11) | 62·7 (0·19) | p < 0·001 | ||||
Rates per 100,000 | 188.7 | 136·5 | 37·4 | 14·8 | |||||
Variable | Count | Percent | Count | Percent | Count | Percent | Count | Percent | p value |
Menopausal surrogate | |||||||||
<50 years | 12,291 | 19.7% | 8,221 | 18·0% | 3,158 | 26·3% | 912 | 18·4% | |
50+ years | 50,258 | 80.3% | 37,350 | 82·0% | 8,858 | 73·7% | 4,050 | 81·6% | p < 0·001 |
Tumor Size | |||||||||
≤ 2.0 cm | 33,906 | 54.2% | 27,257 | 59·8% | 5,316 | 44·2% | 1,333 | 26·9% | |
> 2.0 cm | 24,514 | 39.2% | 17,379 | 38·1% | 6,189 | 51·5% | 946 | 19·1% | |
Other or unknown | 4,129 | 6.6% | 935 | 2·1% | 511 | 4·3% | 2,683 | 54·1% | p < 0·001 |
Lymph nodes | |||||||||
negative | 30,142 | 48.2% | 23,032 | 50·5% | 5,806 | 48·3% | 1,304 | 26·3% | |
positive | 27,055 | 43.3% | 20,549 | 45·1% | 5,590 | 46·5% | 916 | 18·5% | |
Other or unknown | 5,352 | 8.6% | 1,990 | 4·4% | 620 | 5·2% | 2,742 | 55·3% | p < 0·001 |
Tumor Grade | |||||||||
I (low) | 15,966 | 25.5% | 14,621 | 32·1% | 743 | 6·2% | 602 | 12·1% | |
II–III (high) | 33,158 | 53.0% | 23,287 | 51·1% | 8,886 | 74·0% | 985 | 19·9% | |
Other or unknown | 13,425 | 21.5% | 7,663 | 16·8% | 2,387 | 19·9% | 3,375 | 68·0% | p < 0·001 |