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Kinetics of LtxA Binding to Liposomes composed of DPC and N-m-DOPE. The affinity of LtxA for DPC is stronger (by roughly 8 orders of magnitude) than its affinity for N-m-DOPE.
| Lipid | ka (M-1s-1) | kd (s-1) | KD (M) |
|---|---|---|---|
| DPC | 9.5 ( ± 0.6) × 104 | 3.7 ( ± 3.5) × 10-7 | 3.8 ( ± 3.4) × 10-12 |
| N-m-DOPE | 4.5 ( ± 3.8) × 101 | 1.1 ( ± 0.1) × 10-3 | 2.3 ( ± 0.6) × 10-5 |
