Table 3.
Associations between Patient Characteristics and EGFR Mutation, Categorical Variables
| Variable | #positive/# tested | Percentage | Fisher’s Exact p value |
|---|---|---|---|
| Gender | 0.002 | ||
| Male | 16/201 | 8.0% | |
| Female | 53/296 | 17.9% | |
| Race | <0.001 | ||
| African American | 3/63 | 4.8% | |
| Caucasian | 53/388 | 13.7% | |
| Asian American | 10/16 | 65.2% | |
| Hispanic | 0/3 | 0.0% | |
| Other | 2/19 | 10.5% | |
| Race, binary | 0.06 | ||
| African American | 3/63 | 4.8% | |
| Caucasian | 53/388 | 13.7% | |
| Smoking status | <0.001 | ||
| Never Smoker | 42/100 | 42.0% | |
| Ever Smoker | 26/393 | 6.6% | |
| Histology | 0.27 | ||
| Adenocarcinoma | 61/391 | 15.6% | |
| Squamous | 6/44 | 13.6% | |
| Adenosquamous | 0/16 | 0.0% | |
| Poorly Differentiated | 1/30 | 3.3% | |
| Large Cell | 0/9 | 0.0% | |
| Sarcomatoid | 0/1 | 0.0% | |
| Pleomorphic | 0/1 | 0.0% | |
| NOS* | 0/1 | 0.0% | |
| Disease Status | 0.53 | ||
| Localized | 21/137 | 15.3% | |
| Recurrent, extrathoracic | 7/32 | 21.9% | |
| Recurrent, intrathoracic | 6/43 | 14.0% | |
| Metastatic extrathoracic | 23/184 | 12.5% | |
| Metastatic intrathoracic | 10/95 | 10.5% | |
| Subcutaneous Mets | 0.60 | ||
| No | 67/480 | 14.0% | |
| Yes | 0/7 | 0.0% | |
| Surgery as part of treatment | 0.69 | ||
| No | 29/228 | 12.7% | |
| Yes | 37/259 | 14.3% |
*
NOS refers to NSCLC not otherwise specified