Table 5.

Multivariable analysis of EGFR mutation positivity (Exon 19 or L858R Mutation)

Univariate Logistic regression*				Multivariable Logistic regression#
	OR	95% CI	Wald test P value	OR	95% CI	Wald test P value
Gender			0.002			0.03
Male	1.00			1.00
Female	2.52	1.40 - 4.55		2.13	1.10 - 4.15
Race			<0.001			0.01
Caucasian	1.00			1.00
African American	0.32	0.10 - 1.04		0.26	0.07 - 0.93
Asian American	10.54	3.68 - 30.19		5.10	1.41 - 18.41
Hispanic	ND			ND
Other	0.74	0.17 - 3.31		0.22	0.03 - 1.92
Smoking status			<0.001			<0.001
Ever smoker	1.00			1.00
Never smoker	10.22	5.83 - 17.93		9.66	5.27 - 17.71
Charlson index, continuous	0.86	0.76 - 0.97	0.01
Charlson & age, continuous	0.89	0.81 - 0.99	0.03

^*N = 484 with data on all 5 candidate variables seleced by univariate significance (p < 0.10)

^#Best model determined by backward elimination OR = Odds Ratio, CI = Confidence Interval ND = not determined, none of 3 Hispanic patients had EGFR mutations