Table 1. Applications for selected biomarkers*.
Test | IBD vs. Other Disease | UC vs. CD | Risk of Complications | Active Disease vs. Remission | Assess Mucosal Healing | Predict Relapse | Predict Response to Therapy | Therapeutic Adjustment |
---|---|---|---|---|---|---|---|---|
Calprotectin | + | + | + | + | + | |||
Lactoferrin | + | + | + | + | + | |||
S100A12 | + | + | + | + | + | |||
CRP | + | + | + | + | + | |||
ESR | + | + | + | |||||
Serologies | + | + | + | + | ||||
6MP metabolite levels | + | + | + | |||||
Anti-TNF drug levels | + | + | + | |||||
Antibodies against biologic therapies | + | + | + |
The table includes both confirmed and theoretical roles for these biomarkers.