Table 4. Associations of serologies and NOD2 mutations with disease phenotype.
Small bowel disease | Fibrostenosis | Internal Perforation | Small bowel surgery | Perianal disease | |
---|---|---|---|---|---|
ASCA | + | + | + | + | Not associated |
pANCA | - | - | Not associated | - | Not associated |
I2 | + | + | Not associated | + | Not associated |
OmpC | Not associated | + | + | + | Not associated |
Adapted from Mow WS, Vasiliauskas EA, Lin Y-C, Fleshner PR, Papadakis KA, Taylor KD, Landers CJ, Abreu-Martin MT, Rotter JI, Yang H, Targan SR. Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease. Gastroenterology 2004;126:414-24.