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. Author manuscript; available in PMC: 2013 Aug 21.
Published in final edited form as: Gastroenterology. 2011 May;140(6):1817–1826.e2. doi: 10.1053/j.gastro.2010.11.058

Table 5.

Studies associating increased concentrations of fecal calprotectin with relapse in patients with exacerbations in ulcerative colitis.

Author Patient population Duration of remission at entry Calprotectin Concentration to Define Elevated Level Relapse Rate with Low Calprotectin Relapse Rate with High Calprotectin
Gisbert84 UC >6 mos. >150μg/g 9% 31%
Tibble83 UC 1-4 mos. >50μg/g 10%* 85%*
Tibble83 CD 1-4 mos. >50μg/g 15% 85%
Costa82 UC 1-12 mos. >150μg/g 10% 81%
Costa82 CD 1-12 mos. >150μg/g 57% 87%
D'Inca85 UC 3-36 mos. >130μg/g 30% 79%
Sipponen86 UC+CD > 3mos (51% >12 months) >100μg/g 25% 39%
Walkiewicz87# CD Not stated >400μg/g 11% 56%
*

estimated from Kaplan Meier curves